Kinerase Cream SPF 30

Kinerase reviewKinerase gets a lot of hype, and it is very easy to wonder if all that hype is due to the amazing (and very airbrushed) photo of Courtney Cox in their ads. It also sounds very impressive with the active ingredient Kinetin (which they often point out is actually N6-furfuryladenine, I think because it sounds very medical).

What exactly is N6-furfuryladenine? It is a protein, originally derived in 1955 from herring sperm that had been autoclaved (basically baked in an incredibly hot oven). Really. I kid you not. It has also been found in most plants (it is considered a "phytohormone", aka- plant hormone), and in human cells.

Until the mid-1990's it was thought that Kinetin was anti-tumorigenic and that it inhibited growth. Then, someone discovered that it dramatically increases the life span of fruit flies by 65% (not a subtle increase), and retarded their aging by about 25%. Really! Suddenly it became a new "hot" item, and lots of people became to study these anti-aging effects. Over time, it's been found to increase the natural antioxidant activity within tissues like thymus (a big gland in your chest). Kinetin has been found to really affect the way fibroblasts within the dermis age. The fibroblasts retain their "younger" level of collagen production, reproduction of the fibroblasts themselves and their growth rate while in a petri dish. Their life span remains unaffected.

Has all of this amazing sounding research translated into big changes in the skin? Well, if this stuff was absolutely amazing it would be in every product on the market. And, I wouldn't still be telling you that only Retin A has been proven to really fight the signs of aging. There have been small clinical studies (sponsored by the company that used to own Kinerase) that showed that patients with photoaging did have mild improvement in skin texture, mottling and fine wrinkles. As well, moisture retention was improved. But, note that these changes weren't seen until after 24 weeks (6 months!) worth of twice a day application. But, there's a lot of stuff in the anti-aging world that we don't have a lot of evidence for yet, so I'm willing to try pretty much anything!

Complicating all of this even further is Kinetin's difficulty in dissolving into a liquid. It is incredibly picky, and will dissolve into ether, acetone, ethanol as well as some acids and bases, but not into distilled water. Which means that you can't add Kinetin to just anything, it has to be very carefully formulated for the Kinetin to work.

Kinerase, reviewSo, having said all of that, I decided to try this stuff out to see if it lived up to the hype. I tried the Kinerase Cream with SPF 30. I've said in the past that I have combination skin with occasional small break outs, so if anything I was worried that a cream would be way too hydrating for my skin.

I'm just going to come right out and say that I did not like this cream at all. It isn't silky during application (I think I'm a bit too used to silicone in my products), and it is difficult to spread evenly. It is not hydrating. Not one bit. I was left with dry and uncomfortable cheeks every day while using this creme. Worst of all, I had to stop using it within five days. I suddenly had large, cystic blemishes on my forehead, next to my nose and on my chin. I've never had blemishes like this before, and these appeared suddenly about two days after I started using the Kinerase.

It took my skin a full month to recover from five days of Kinerase! I have to say that this cream is definitely on my Do Not Recommend list.

If you would like to try Kinetin, but in a cheaper or alternative form, it is also available in lotions from Almay and The Body Shop.

Active Ingredients:
• Titanium Dioxide 6%
• Ethylhexyl Methoxycinnamate 7%

Inactive Ingredients: Purified Water, C12-15 Alkyl Benzoate, Ethoxydiglycol, Cyclopentasiloxane, Glycerin, Caprylic/Capric Triglycerides, Stearic Acid, Dimethicone, Cetyl Alcohol, Silica, Phenoxyethanol, Peg-100 Stearate, Glyceryl Stearate, Alumina, Peg-12 Glyceryl Distearate, Sorbitan Stearate, Sodium Hexamethaphosphate, Triethanolamine, Methylparaben, Carbomer, Disodium EDTA, Camellia Sinensis Leaf Extract, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Propylparaben, Pyris Communis (Pear) Fruit Extract, Kinetin, Hibiscus Sabdariffa Flower Extract, Ferula Assa Foetida Root Extract, Ethylparaben, Laminaria Digitata (Algae) Extract, Ammonium Acryloyldimethyltaurate/VP Copolymer, Butylparaben.

***A quick warning about Kinerase- There is a warning on Kinerase that it is not pregnancy safe.


  1. Wow...great review. I've been wondering if Kinerase is worth all the Courteney hype. I'll be sure to pass on this one.

  2. Oh my gosh! I just read your review and I think I had a similar experience. I think I have a similar skin type as yours, and I received a sample of the Kinerase cream with a recent order. I tried it out, thinking "no problem" (most creams don't bother my skin) and my face has erupted with huge blemishes over the past week, in places that I usually don't get them. It is taking them forever to go away! It took me a couple days to realize that it was the Kinerase. Into the trash it goes!

  3. Well done research. I have been using Kinerase now for a while and get it from my dermatologist. While I agree with you on the moisturization ability of this product, for me, it still protects my skin from the rays. I pay no attention to Courteney's claims - again, I used this product before she ever came on board with Kinerase. There are other really good products in their line to try - I really recommend the Ultimate Day and Night if you have dryer skin and the at home peel which has done wonders for my skin tone.

    As for the cheaper products. I did research on those - fact is that Kinerase uses a higher amount of the Kinetin than the store bought products. I think the results I have gotten from using Kinerase for over 6 years has made my mind up and hope all of you get the chance to try one of their basic moisturizers. I do hope that the company can find a way to improve their sunscreen formulas though.

  4. This is a very fair review of Kinerase with a lot of good research behind it. It seems to me that there are better products out there than accomplish the same things in a lower price than what Kinerase does.

  5. I have to tell you that I have been using Kinerase Lotion for about 4 years now. I got my first samples from my Ob/Gyn office and decided to give it a try. I have combination skin with a slight ruddiness and occasional break outs in the T-Zone area. This Lotion has been a miracle for me. It's not advertised as a "moisturizer" so those expecting it to moisturize will be disappointed. However, it does sufficiently moisturize my skin and I don't need to use any other moisturizers at all. Also, it completely took away brown age spots around my eyes (from sun damage) and evened out my skin tone. People that I haven't seen in a few years think I've had a face lift because I look so much younger and my skin just glows. I think it's definitely due to the use of Kinerase over the years. I have tried other "high end" products including, Le Mer, Strivectin, Chanel, Clarins, etc... and I always go back to the Kinerase. And you can buy Kinerase on-line for about $50 less than Nordstrom's sells it for. I just bought 5 80g tubes for $49 each (normally $75 - $110)through a skin care company in Canada (they had a blowout sale). My daughter is 26 and also started using the Kinerase Lotion and Face Wash and loves both products.

  6. I have been using Kinerase Cream (NO sunscreen) for about a year and a half now. I cannot tell you how much I LOVE this cream. I agree with previous post...I am now 40 (ugh) and this cream truly evened out my skin tone, faded spots, redness and uneveness (I am not afraid to go out of the house without foundation)and since using it I stopped getting random breakouts that have haunted me since teenage years. I will never buy another another cream. For me, I have had amazing results!

  7. I just have to say that Kinerase Cream has worked wonderfully on my skin. I work for a cosmetic retailer that sells many different lines of make-up and skincare, so I have tried everything. Kinerase is the best line I have yet to find. I get so many compliments on my skin and I tell my clients exactly what I use. I'm in my late 20's and I will keep using my Kinerase for many years to come God willing.

  8. I completely agree with those who love this product. I bought the lotion instead of the cream because I tend toward breakouts. I have had bumpy skin with some larger permanent bumps (even while using Retin-A). I decided to try Kinerase before spending the money to go to the dermatologist to have the bumps diagnosed. I've been using the lotion for a week and half of the bumps are already gone. The others are smaller.

  9. I just wanted to let everyone know that I've officially CLOSED the comments for this post. I actually stopped publishing any new comments for this post about 3-4 months ago. Every few days there is a sudden rush of comments for this post, very similarly worded, very positive, and all from the same town. The whole thing is very fishy.

    Anyways, this post is meant to only describe evidence for the product in the scientific part of the review and then my own personal experience with the product, which was bad. It very well might be that my skin didn't like this particular formulation, I don't know.


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